Browsing Doctorado by Author "Peralta Arrieta, Irlanda"
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DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
Peralta Arrieta, Irlanda; Hernández Sotelo, Daniel; Castro Coronel, Yaneth; Leyva Vazquez, Marco Antonio; Illades_Aguiar, Berenice (American Journal of Cancer Research, 2017-01)Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ... -
Efecto de la sobre-expresión de DNMT3B en la actividad transcripcional de genes relacionados con el cáncer
Peralta Arrieta, Irlanda (Universidad Autónoma de Guerrero (México), 2016-10)Introduction: DNMT3B, de novo DNA methyltransferase, is frequently overexpressed in cancer. This event is associated with abnormal methylation of tumor suppressor and DNA repair genes, favoring the development and progression ...