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Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions

Torres Rojas, Francisco Israel; Alarcón Romero, Luz Del Carmen; Leyva Vazquez, Marco Antonio; Ortiz Ortiz, Julio; Mendoza Catalán, Miguel Ángel; Hernández Sotelo, Daniel; Del Moral Hernández, Oscar; Rodríguez Ruiz, Hugo Alberto; Leyva Illades, Dinorah; Flores Alfaro, Eugenia; Illades_Aguiar, Berenice (Oncology Letters, 2017-09-13)

High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ...

miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer

Campos Viguri, Gabriela Elizabeth; Jiménez Wences, Hilda; Torres Altamirano, Gricenda; Hernández Sotelo, Daniel; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Fernandez Tilapa, Gloria (Infectious Agents and Cancer, 2015-01)

The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ...