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DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation

Peralta Arrieta, Irlanda; Hernández Sotelo, Daniel; Castro Coronel, Yaneth; Leyva Vazquez, Marco Antonio; Illades_Aguiar, Berenice (American Journal of Cancer Research, 2017-01)

Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ...

Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)

Jiménez Wences, Hilda; Peralta Zaragoza, Oscar; Fernandez Tilapa, Gloria (2014-03-13)

Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus ...