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dc.contributor.authorSerafín Higuera, Idanya Rubí
dc.contributor.authorGaribay Cerdenares, Olga Lilia
dc.contributor.authorIllades_Aguiar, Berenice
dc.contributor.authorFlores Alfaro, Eugenia
dc.contributor.authorJiménez López, Marco Antonio
dc.contributor.authorSierra Martínez, Pavel
dc.contributor.authorAlarcón Romero, Luz Del Carmen
dc.creatorSerafín Higuera, Idanya Rubí; 273381
dc.creatorGaribay Cerdenares, Olga Lilia; 210645
dc.creatorIllades_Aguiar, Berenice;#0000-0003-3937-335X
dc.creatorFlores Alfaro, Eugenia; 224947
dc.creatorJiménez López, Marco Antonio; 706226
dc.creatorSierra Martínez, Pavel; 122029
dc.creatorAlarcón Romero, Luz Del Carmen; 259901
dc.date.accessioned2019-04-04T00:01:59Z
dc.date.available2019-04-04T00:01:59Z
dc.date.issued2016-09-05
dc.identifier.issn0099-2240
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/393
dc.description.abstractCervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are several diagnosis methods of CC; among the most frequents are the conventional Pap cytology (Pap), colposcopy, and visual inspection with acetic acid (VIA), histopathological examination, tests of imaging and detection of high-risk papilloma virus (HR-HPV) with molecular tests (PCR, hybridization, sequencing). Proteomics is a tool for the detection of new biomarkers that can be associated with clinical stage, histological type, prognosis, and/or response to treatment. In this study we performed a comparative analysis of CC cells with normal cervical cells. The proteomic analysis was carried out with the fluorescent two-dimensional electrophoresis (2D-DIGE) technique to subsequently identify differential protein profiles using Decyder Software, and the selected proteins were identified by Mass Spectrometry (MALDI-TOF).
dc.description.sponsorshipWe thank the strengthening program graduate high with file number: I010/455/2013 C- 677/2013 of UAGro. Serafín-Higuera I was recipient of a Doctoral fellowship with file number 222252 from CONACYT, México.
dc.formatpdf
dc.language.isoeng
dc.publisherProteome Science
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectTesauro europeo para la promoción de la salud /Cervical cáncer
dc.subjectCAB Thesaurus /Human Papilloma
dc.subjectCAB Thesaurus /Virus
dc.subjectCAB Thesaurus /Proteomics
dc.subjectCAB Thesaurus /Mass spectrometry
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::BIOLOGÍA HUMANA::PROTEÍNAS
dc.titleDifferential proteins among normal cérvix cells and cervical cancer cells with HPV-16 infection, through mass spectrometrybased Proteomics (2D-DIGE) in women from Southern México
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||2410||230227
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro08202325
dc.identifier.doihttps://doi.org/10.1186/s12953-016-0099-4


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