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dc.contributor.authorZubillaga Guerrero, Ma. Isabel
dc.contributor.authorAlarcón Romero, Luz Del Carmen
dc.contributor.authorIllades_Aguiar, Berenice
dc.contributor.authorFlores Alfaro, Eugenia
dc.contributor.authorPeralta Zaragoza, Oscar
dc.creatorZubillaga Guerrero, Ma. Isabel; 333988
dc.creatorAlarcón Romero, Luz Del Carmen; 259901
dc.creatorIllades_Aguiar, Berenice;#0000-0003-3937-335X
dc.creatorFlores Alfaro, Eugenia; 224947
dc.creatorPeralta Zaragoza, Oscar; 122021
dc.date.accessioned2019-04-04T00:01:59Z
dc.date.available2019-04-04T00:01:59Z
dc.date.issued2015-09-30
dc.identifier.issn1940-5901
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/394
dc.description.abstractMicroRNAs are involved in diverse biological processes through regulation of gene expression. The microRNA profile has been shown to be altered in cervical cancer (CC). MiR-16-1 belongs to the miR-16 cluster and has been implicated in various aspects of carcinogenesis including cell proliferation and regulation of apoptosis; however, its function and molecular mechanism in CC is not clear. Cyclin E1 (CCNE1) is a positive regulator of the cell cycle that controls the transition of cells from G1 to S phase. In CC, CCNE1 expression is frequently upregulated, and is an indicator for poor outcome in squamous cell carcinomas (SCCs)
dc.description.sponsorshipInstitute of Public Health from México (INSP) and it received funding sources from INSP, as well as from the National Council of Science and Technology (CONACYT) with file numbers: SALUD-2008-01-87130, SALUD-2009-01-111-892 and CB-2011-01-169209. We also thank the strengthening program graduate high with file number: I010/455/2013 C-677/2013.
dc.formatpdf
dc.language.isoeng
dc.publisherInternational Journal of Clinical and Experimental Medicine
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4
dc.subjectTesauro de la UNESCO /Cervical cancer
dc.subjectTesauro de la UNESCO /Human papilloma virus
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::PATOLOGÍA::CARCINOGÉNESIS
dc.titleMicroRNA miR-16-1 regulates CCNE1 (cyclin E1) gene expression in human cervical cancer cells
dc.typeArtículo
dc.contributor.committeeMemberBermúdez Morales, Victor Hugo
dc.contributor.committeeMemberDeas, Jessica
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3207||320703
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro09033503


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