Two SNPs in the region 3 UTR of resistin gene have been detected. In this work the SNP +62G/A was associated with DMT2 and hypertension. The variants were identified by PCR and RFLPs in 272 subjects; the groups included SM, DMT2 and normal control subjects. RESULT: The GG variant was predominant (78) over the AA variant (22). The allelic frequency +62A, was: 0.664 in DMT2 and 0.363 in SM compared with control subjects (0.401).