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Mostrando ítems 11-20 de 170
Variantes genéticas en FPGS y GGH y su asociación con la respuesta y toxicidad al tratamiento con metotrexato en pacientes con artritis reumatoide.
(Universidad Autónoma de Guerrero (México), 2019-12)
Methotrexate (MTX) is a safe and effective drug used to treatment of rheumatoid arthritis (RA), however, some patients have a poor therapeutic response or adverse and toxic manifestations related to MTX use. It has been ...
Efecto de la disminución de HOTAIR en la metilación y expresión de los genes CDH3, ITGA8, HLA-DRA y VCAM1, que participan en adhesión celular, en la línea celular HeLa.
(Universidad Autónoma de Guerrero (México), 2020-01)
The lncRNA HOTAIR regulates gene expression through DNA methylation. HOTAIR is overexpressed in cervical cancer and modulates migration, invasion, proliferation, and apoptosis among other cellular processes. The migration ...
Perfil proteómico de exosomas secretados por macrófagos U937 DC-SIGN infectados con DENV-2 y efecto del contenido exosomal en la replicación viral.
(Universidad Autónoma de Guerrero (México), 2020-01)
Dengue is a disease caused by dengue virus. Dendritic cells, monocytes and macrophages, are mainly infected by this virus and these cells release exosomes during infection. Exosome secretion by cells infected by the DENV ...
Expresión de miR-26b, miR-100 y uno de sus genes blanco en células de leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2020-01)
MicroRNAs participate in the regulation of gene expression in multiple cellular processes, including leukemogenesis. miR-26b and miR-100 in acute lymphoblastic leukemia (ALL) have a deregulation in their expression. The ...
Efecto de E7 de referencia y de su variante C732/C789/G795 del VPH 16 sobre la expresión de las Isoformas de OCT4.
(Universidad Autónoma de Guerrero (México), 2019-12)
High-risk Human Papillomavirus (HPV-AR), such as HPV16, has been associated with the development of cervical cancer (CaCU). Several studies suggest that specific variations in the sequence of its oncogenes such as HPV E7 ...
Evaluación de la línea celular Huh7 como modelo de resistencia a la insulina determinado por diversos biomarcadores en comparación con HepG2.
(Universidad Autónoma de Guerrero (México), 2020-01)
Insulin resistance (RI) is defined as the inability of insulin to internalize glucose in its target cells, favoring the development of metabolic diseases. The liver plays an important role in the development of RI; hence, ...
Efecto de la metformina sobre marcadores bioquímicosmoleculares y secreción de exosomas en células HUH7 con resistencia a insulina.
(Universidad Autónoma de Guerrero (México), 2020-01)
Liver-specific insulin resistance is associated with the development of the main challenges in metabolism resulting in dyslipidemia, hyperinsulinemia and hyperglycemia. In vitro models developed for researching the hepatic ...
El extracto de ajo envejecido aumenta la expresión de GLUT-1 en neuronas y astrocitos en isquemia cerebral
(Universidad Autónoma de Guerrero (México), 2011-12)
Focal impairment of cerebral blood flow during stroke restricts the delivery of oxygen and glucose with consequent depletion in neuronal energy levels. In cerebral ischemia models it has been demonstrated that mitochondrial ...
Interacción de la dieta con la microbiota intestinal y su relación con el perfil metabólico en jóvenes con obesidad y normopeso
(Universidad Autónoma de Guerrero (México), 2017-01)
Background: The gut microbiota is considered to be an "organ", because it meets host's structural functions, it contributes in the development of the immune system and metabolism. It has been found that bacteria in the gut ...
Péptidos recombinantes de Trypanosoma cruzi y su utilidad en el diagnóstico de la enfermedad de chagas en el Estado de Guerrero
(Universidad Autónoma de Guerrero (México), 2008-10)
Background: Diagnosis of Chagas disease is based on serological methods with high occurrence of false positive. The use of recombinant antigens is recommended to increase the sensitivity and specificity of serological ...