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Mostrando ítems 1-6 de 6
Metilación del gen L1 e integración de VPH-AR en citología normal, lesiones precancerosas y CaCU y efecto de E6 en la metilación de genes relacionados a cáncer
(Universidad Autónoma de Guerrero (México), 2017-01)
Cervical cancer (CaCU) is the third most common neoplasm among women, whose causative agent is the human papillomavirus (HPV). HPV 16 and 18 are most frequently associated with this malignancy. Viral integration is a ...
Estudio de variantes del número de copias en genes candidato asociados a obesidad infantil
(Universidad Autónoma de Guerrero (México), 2017-02)
Obesity is one of the major health problems in the world, in Mexico the combined prevalence of overweight and obesity in school-age children is 34.4%. The weight gain starts during childhood, in its origin, environmental ...
Análisis de marcadores de la transición epiteliomesénquima en células de epitelio mamario no tumoral en respuesta a leptina.
(Universidad Autónoma de Guerrero (México), 2017-10)
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
(American Journal of Cancer Research, 2017-01)
Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ...
Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions
(Oncology Letters, 2017-09-13)
High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ...
Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
(Clin Exp Pathol, 2017-10-15)
Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ...