ListarTesis por tema "BIOLOGÍA Y QUÍMICA::QUÍMICA::BIOQUÍMICA"
Mostrando ítems 1-15 de 15
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Análisis de la expresión de pRb en células transfectadas con E7 de VPH 16 prototipo y sus variantes E7-A712, E7-G647/C789/G795 y E7-C732/C789/G795.
(Universidad Autónoma de Guerrero (México), 2020-12)HPV 16 is the pathogen most associated with cervical cancer, a disease in which the overexpression of the viral oncoprotein E7 plays an essential role because its main targets are proteins involved in the regulation of the ... -
Cambios morfológicos y expresión de ROR¿t y UBR5 en células mononucleares humanas infectadas con H. pylori.
(Universidad Autónoma de Guerrero (México), 2020-01)H. pylori infection induces morphological alterations of gastric epithelial cells, infiltration of mononuclear cells and increase in the number of Th17 cells. Reported data show an increase in IL-17A due to the activation ... -
Efecto crónico del cadmio sobre marcadores de transición epitelio-mesenquimal en células de epitelio mamario no tumoral.
(Universidad Autónoma de Guerrero (México), 2019-11)Breast cancer (BC) is the most frequent neoplasia and leading cause of death in Mexican and worldwide women. Besides the well-known risk factors, the exposure to environmental hazards such as cadmium (Cd) is currently been ... -
Efecto de E7 de referencia y de su variante C732/C789/G795 del VPH 16 sobre la expresión de las Isoformas de OCT4.
(Universidad Autónoma de Guerrero (México), 2019-12)High-risk Human Papillomavirus (HPV-AR), such as HPV16, has been associated with the development of cervical cancer (CaCU). Several studies suggest that specific variations in the sequence of its oncogenes such as HPV E7 ... -
Efecto de la disminución de HOTAIR en la metilación y expresión de los genes CDH3, ITGA8, HLA-DRA y VCAM1, que participan en adhesión celular, en la línea celular HeLa.
(Universidad Autónoma de Guerrero (México), 2020-01)The lncRNA HOTAIR regulates gene expression through DNA methylation. HOTAIR is overexpressed in cervical cancer and modulates migration, invasion, proliferation, and apoptosis among other cellular processes. The migration ... -
Efecto de la metformina sobre marcadores bioquímicosmoleculares y secreción de exosomas en células HUH7 con resistencia a insulina.
(Universidad Autónoma de Guerrero (México), 2020-01)Liver-specific insulin resistance is associated with the development of the main challenges in metabolism resulting in dyslipidemia, hyperinsulinemia and hyperglycemia. In vitro models developed for researching the hepatic ... -
Efecto del resveratrol sobre la hiperfagia y la expresión del receptor de grelina (GHSR-1a) en núcleo arcuato de ratas diabéticas.
(Universidad Autónoma de Guerrero (México), 2020-01)Hyperphagia is a classic manifestation in diabetes mellitus (DM), although there are first-line drugs that improve various symptoms of the disease, there is currently no medication capable of controlling hyperphagic behavior. ... -
Estudio longitudinal de la composición corporal y del perfil metabólico en personas positivas para Adenovirus 36.
(Universidad Autónoma de Guerrero (México), 2019-12)Infectobesity refers to the implication that some microorganisms have in the development of obesity. Adenovirus 36 (Ad-36) has been linked to obesity in studies in human and animal models. Aim: We evaluated the relationship ... -
Evaluación de la línea celular Huh7 como modelo de resistencia a la insulina determinado por diversos biomarcadores en comparación con HepG2.
(Universidad Autónoma de Guerrero (México), 2020-01)Insulin resistance (RI) is defined as the inability of insulin to internalize glucose in its target cells, favoring the development of metabolic diseases. The liver plays an important role in the development of RI; hence, ... -
Expresión de adiponectina, leptina y resistina en tejido adiposo y su relación con la resistencia a la insulina en mujeres con y sin Ad-36.
(Universidad Autónoma de Guerrero (México), 2020-01)Insulin resistance, is a metabolic disorder that occurs primarily in obesity, due to deficient insulin signaling. Adenovirus 36 (Ad-36) has been reported to increase adipogenesis, but positively regulates the distal signaling ... -
Expresión de HP0605 y HP0971 de bombas de eflujo en cepas de Helicobacter pylori resistentes a claritromicina aisladas de pacientes con patología gástrica.
(Universidad Autónoma de Guerrero (México), 2020-01)In recent years there has been an increase in the prevalence of Helicobacter pylori infection in different regions, mainly associated with the increase in strains resistant to different antibiotics. The most important drug ... -
Expresión de miR-26b, miR-100 y uno de sus genes blanco en células de leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2020-01)MicroRNAs participate in the regulation of gene expression in multiple cellular processes, including leukemogenesis. miR-26b and miR-100 in acute lymphoblastic leukemia (ALL) have a deregulation in their expression. The ... -
miR-24-3p y miR-142-3p: Expresión en pacientes con patología gástrica y relación con PKC en macrófagos humanos infectados por Helicobacter pylori.
(Universidad Autónoma de Guerrero (México), 2020-01)H. pylori is the main cause of chronic gastritis and gastric cancer. In response to H. pylori, monocytes and macrophages are accumulate in the gastric mucosa, however, the bacteria is resistant to death by these cells. H. ... -
Perfil proteómico de exosomas secretados por macrófagos U937 DC-SIGN infectados con DENV-2 y efecto del contenido exosomal en la replicación viral.
(Universidad Autónoma de Guerrero (México), 2020-01)Dengue is a disease caused by dengue virus. Dendritic cells, monocytes and macrophages, are mainly infected by this virus and these cells release exosomes during infection. Exosome secretion by cells infected by the DENV ... -
Variantes genéticas en FPGS y GGH y su asociación con la respuesta y toxicidad al tratamiento con metotrexato en pacientes con artritis reumatoide.
(Universidad Autónoma de Guerrero (México), 2019-12)Methotrexate (MTX) is a safe and effective drug used to treatment of rheumatoid arthritis (RA), however, some patients have a poor therapeutic response or adverse and toxic manifestations related to MTX use. It has been ...